Saxenda Benefits

Typically, weight loss starts in the first few weeks after starting Saxenda and can level off after several months, notes Dr. Kipnis. More specific weight loss benefits include:

Weight Loss in Adults

In a phase 3 clinical trial funded by Novo Nordisk, 63% of individuals receiving 3 milligrams of liraglutide lost 5% or more of total body weight over 56 weeks (versus 27% of patients in the placebo group). The study included 3,731 adults with obesity or overweight with high cholesterol or high blood pressure. Of note, treatment and placebo groups both received counseling regarding lifestyle modifications.^[1]

Weight Loss in Adolescents

Phase 3 pediatric clinical studies (also sponsored by Novo Nordisk) showed a significant average BMI reduction in 12 to 17 year olds living with obesity receiving Saxenda, while the placebo group had no change. In addition, the Saxenda group lost on average 2.65% of body weight, while the placebo group actually gained an average of 2.37% of their body weight. One important caveat to note about the study, according to Dr. Mann, is that the “weight loss seen with Saxenda in [pediatric] clinical trials occurred along with intensive counseling about nutrition and exercise therapy.”

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