Saxenda Side Effects

Gastrointestinal side effects are the most common Saxenda side effects, but they tend to subside over time. Common side effects reported in 5% or more of adults taking Saxenda in clinical trials include:

  • Nausea or vomiting
  • Diarrhea or constipation
  • Injection site reaction
  • Headache
  • Hypoglycemia (low blood sugar) in individuals with type 2 diabetes
  • Indigestion
  • Fatigue
  • Dizziness
  • Increased lipase
  • Upper abdominal pain

Saxenda has a black box warning for medullary thyroid cancer based on associations found in animal studies. It is unclear whether this risk applies to humans. Additional serious side effects reported with Saxenda include:

  • Thyroid tumors
  • Acute pancreatitis
  • Gallbladder disease
  • Renal impairment
  • Allergic reaction
  • Racing heartbeat
  • Suicidal behavior and ideation

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